2025 NFL Week 12 odds, betting: Full list of Week 12 spreads
The 2025-26 NFL regular season is past the midway point, and Week 11 saw plenty of upsets as favorites have gone 5-9 against the spread with four outright losses — with the Monday Night Football game still to be played.
It's never too early to look ahead to next week, though, and sportsbooks have already posted lines for every matchup.
Here are the odds for every Week 12 NFL game at BetMGM:
Thursday
Buffalo Bills (-4, 43.5) at Houston Texans
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Sunday
1 p.m. ET
Minnesota Vikings at Green Bay Packers (-6, 42)
Pittsburgh Steelers at Chicago Bears (-3, 45.5)
New England Patriots (-7, 50.5) at Cincinnati Bengals
New York Giants at Detroit Lions (-11.5, 49.5)
Seattle Seahawks (-13, 41.5) at Tennessee Titans
Indianapolis Colts at Kansas City Chiefs (-3.5, 49.5)
New York Jets at Baltimore Ravens (-14, 44.5)
4 p.m. ET
Cleveland Browns at Las Vegas Raiders (-3, 37.5)
Jacksonville Jaguars (-2.5, 47.5) at Arizona Cardinals
Philadelphia Eagles (-4.5, 50.5) at Dallas Cowboys
Atlanta Falcons (-1.5, 40) at New Orleans Saints
Sunday Night Football
Tampa Bay Buccaneers at Los Angeles Rams (-6.5, 49.5)
Monday
Carolina Panthers at San Francisco 49ers (-6.5, 47.5)
Bye-week teams: Broncos, Dolphins, Chargers, Commanders